{"id":5995,"date":"2024-09-26T15:21:18","date_gmt":"2024-09-26T19:21:18","guid":{"rendered":"https:\/\/als-ny.org\/?p=5995"},"modified":"2024-12-06T10:50:22","modified_gmt":"2024-12-06T15:50:22","slug":"early-signs-of-als-in-females-a-detailed-insight","status":"publish","type":"post","link":"https:\/\/als-ny.blackbaudwp.com\/es\/early-signs-of-als-in-females-a-detailed-insight\/","title":{"rendered":"Signos tempranos de ELA en mujeres: una perspectiva detallada"},"content":{"rendered":"<br \/>\n<style>\n    \/* Base styles *\/\n    body {\n    font-family: Arial, Georgia;\n    line-height: 1.6;\n    color: #333;\n    margin: 0;\n    padding: 0;\n    font-size: 16px;\n    }\n    .flex-container {\n    display: flex;\n    flex-wrap: wrap;\n    gap: 20px;\n    margin-bottom: 20px;\n    }\n    #toc, #summary {\n    color: #ffffff;\n    padding: 20px;\n    border-radius: 10px;\n    font-weight: normal;\n    flex: 1;\n    min-width: 250px;\n    }\n    #toc {\n    background-color: #737b4c;\n    }\n    #summary {\n    background-color: #7A6855;\n    }\n    .key-takeaways, #references {\n    background-color: #737b4c;\n    color: #ffffff;\n    padding: 20px;\n    border-radius: 10px;\n    margin-bottom: 20px;\n    font-weight: normal;\n    }\n    #references {\n    background-color: #005776;\n    }\n    #toc a, #references a {\n    color: #ffffff;\n    font-weight: normal;\n    }\n    #toc ul {\n    list-style-type: none;\n    padding-left: 0;\n    }\n    #toc details ul {\n    padding-left: 20px;\n    }\n    #toc summary {\n    cursor: pointer;\n    display: flex;\n    align-items: center;\n    list-style: none;\n    }\n    #toc summary::-webkit-details-marker {\n    display: none;\n    }\n    #toc summary::before {\n    content: '+';\n    display: inline-block;\n    width: 15px;\n    text-align: center;\n    margin-right: 5px;\n    transition: transform 0.3s ease;\n    }\n    #toc details[open] > summary::before {\n    content: '-';\n    transform: rotate(180deg);\n    }\n    .callout {\n    color: white;\n    padding: 20px;\n    font-size: 1.5em;\n    line-height: 1.4;\n    text-align: center;\n    border-radius: 10px;\n    box-shadow: 0 4px 8px rgba(0, 0, 0, 0.1);\n    width: 100%;\n    margin: 20px 0;\n    overflow: hidden;\n    }\n    .callout-color1 {\n    background-color: #E0601F;\n    }\n    .callout-color2 {\n    background-color: #FDB515;\n    }\n    \/* Responsive design *\/\n    @media screen and (min-width: 768px) {\n    body {\n    font-size: 18px;\n    }\n    .callout {\n    width: calc(50% - 10px);\n    font-size: 1.75em;\n    }\n    .callout-right {\n    float: right;\n    margin-left: 20px;\n    }\n    .callout-left {\n    float: left;\n    margin-right: 20px;\n    }\n    }\n    @media screen and (max-width: 767px) {\n    body {\n    font-size: 16px;\n    }\n    h1 {\n    font-size: 1.5em;\n    }\n    h2 {\n    font-size: 1.25em;\n    }\n    h3 {\n    font-size: 1.12em;\n    }\n    .callout {\n    font-size: 1.12em;\n    }\n    #toc, #summary, .key-takeaways, #references {\n    padding: 15px;\n    }\n    .flex-container {\n    flex-direction: column;\n    }\n    }\n    \/* Ensure images are responsive *\/\n    img {\n    max-width: 100%;\n    height: auto;\n    }\n    \/* Improve table responsiveness *\/\n    table {\n    width: 100%;\n    border-collapse: collapse;\n    overflow-x: auto;\n    display: block;\n    }\n    \/* Ensure proper spacing and readability *\/\n    p, ul, ol {\n    margin-bottom: 1em;\n    }\n    \/* Improve form element responsiveness if any *\/\n    input, select, textarea {\n    max-width: 100%;\n    }\n    <\/style>\n<p><!--START JSON+LD --><br \/>\n<script type=\"application\/ld+json\">\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"Article\",\n  \"mainEntityOfPage\": {\n    \"@type\": \"WebPage\",\n    \"@id\": \"https:\/\/als-ny.blackbaudwp.com\/early-signs-of-als-in-females\"\n  },\n  \"headline\": \"Early Signs of ALS in Females: A Comprehensive Guide\",\n  \"description\": \"Explore the early signs of ALS in females, including bulbar-onset symptoms, limb-onset symptoms, and cognitive changes. Learn about gender differences in ALS presentation and the challenges faced in diagnosis and management.\",\n  \"image\": \"https:\/\/als-ny.blackbaudwp.com\/images\/early-signs-als-females.jpg\",\n  \"author\": {\n    \"@type\": \"Organization\",\n    \"name\": \"ALS United Greater New York\",\n    \"url\": \"https:\/\/als-ny.blackbaudwp.com\"\n  },\n  \"publisher\": {\n    \"@type\": \"Organization\",\n    \"name\": \"ALS United Greater New York\",\n    \"logo\": {\n      \"@type\": \"ImageObject\",\n      \"url\": \"https:\/\/als-ny.blackbaudwp.com\/logo.png\"\n    }\n  },\n  \"datePublished\": \"2024-03-15T09:00:00-05:00\",\n  \"dateModified\": \"2024-03-15T09:00:00-05:00\",\n  \"speakable\": {\n    \"@type\": \"SpeakableSpecification\",\n    \"cssSelector\": [\n      \"#summary\",\n      \"#Section_1\",\n      \"#Section_2\",\n      \"#Section_3\",\n      \"#Section_4\",\n      \"#Section_5\",\n      \"#conclusion\"\n    ]\n  },\n  \"hasPart\": [\n    {\n      \"@type\": 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\"https:\/\/my.clevelandclinic.org\/health\/diseases\/16729-amyotrophic-lateral-sclerosis-als\"\n    }\n  ],\n  \"isPartOf\": {\n    \"@type\": \"WebSite\",\n    \"name\": \"ALS United Greater New York\",\n    \"url\": \"https:\/\/als-ny.blackbaudwp.com\"\n  },\n  \"inLanguage\": \"en-US\",\n  \"license\": \"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/\",\n  \"accessMode\": \"textual\",\n  \"accessModeSufficient\": \"textual\",\n  \"accessibilityFeature\": [\"alternativeText\", \"tableOfContents\"],\n  \"accessibilityHazard\": \"noFlashingHazard\",\n  \"audience\": {\n    \"@type\": \"Audience\",\n    \"audienceType\": \"General public, ALS patients, caregivers, and healthcare professionals\"\n  }\n}\n<\/script><\/p>\n<p><!--END JSON+LD --><\/p>\n<div class=\"flex-container\">\n<div id=\"toc\"><b>Table of Contents<\/b><\/p>\n<ul>\n<li><a href=\"#summary\">Summary<\/a><\/li>\n<li>\n<details>\n<summary><a href=\"#Section_1\">Understanding ALS: An Overview<\/a><\/summary>\n<ul>\n<li><a href=\"#Section_1_SubSection_1\">Prevalence and Demographics of ALS<\/a><\/li>\n<li><a href=\"#Section_1_SubSection_2\">The Importance of Early Detection in ALS Management<\/a><\/li>\n<\/ul>\n<\/details>\n<\/li>\n<li>\n<details>\n<summary><a href=\"#Section_2\">Early Signs of ALS in Females: A Detailed Insight<\/a><\/summary>\n<ul>\n<li><a href=\"#Section_2_SubSection_1\">Bulbar-Onset Symptoms: Speech and Swallowing Difficulties<\/a><\/li>\n<li><a href=\"#Section_2_SubSection_2\">Limb-Onset Symptoms: Weakness and Coordination Issues<\/a><\/li>\n<li><a href=\"#Section_2_SubSection_3\">Cognitive and Emotional Changes in Early-Stage ALS<\/a><\/li>\n<\/ul>\n<\/details>\n<\/li>\n<li>\n<details>\n<summary><a href=\"#Section_3\">Gender Differences in ALS Presentation<\/a><\/summary>\n<ul>\n<li><a href=\"#Section_3_SubSection_1\">Comparing Symptom Onset Between Males and Females<\/a><\/li>\n<li><a href=\"#Section_3_SubSection_2\">Hormonal Influences on ALS Progression in Women<\/a><\/li>\n<li><a href=\"#Section_3_SubSection_3\">Genetic Factors Affecting ALS Development in Females<\/a><\/li>\n<\/ul>\n<\/details>\n<\/li>\n<li>\n<details>\n<summary><a href=\"#Section_4\">Diagnostic Challenges for ALS in Women<\/a><\/summary>\n<ul>\n<li><a href=\"#Section_4_SubSection_1\">Distinguishing ALS Symptoms from Other Neurological Conditions<\/a><\/li>\n<li><a href=\"#Section_4_SubSection_2\">The Role of Medical History and Physical Examinations<\/a><\/li>\n<li><a href=\"#Section_4_SubSection_3\">Advanced Diagnostic Tools and Tests for Confirming ALS<\/a><\/li>\n<\/ul>\n<\/details>\n<\/li>\n<li>\n<details>\n<summary><a href=\"#Section_5\">Support and Management for Women with Early ALS<\/a><\/summary>\n<ul>\n<li><a href=\"#Section_5_SubSection_1\">Multidisciplinary Care Approaches for ALS Patients<\/a><\/li>\n<li><a href=\"#Section_5_SubSection_2\">Lifestyle Adaptations and Assistive Technologies<\/a><\/li>\n<li><a href=\"#Section_5_SubSection_3\">Emotional Support and Mental Health Resources<\/a><\/li>\n<\/ul>\n<\/details>\n<\/li>\n<li><a href=\"#conclusion\">Conclusion<\/a><\/li>\n<li><a href=\"#references\">References<\/a><\/li>\n<\/ul><\/div>\n<div id=\"summary\"><b>Summary<\/b><\/p>\n<p>At ALS United Greater New York, we&#8217;re committed to empowering our community with knowledge about Amyotrophic Lateral Sclerosis (ALS). This guide focuses on the early signs of ALS in females, highlighting the importance of early detection and the unique challenges women face in diagnosis and management.<\/p>\n<\/p><\/div>\n<\/div>\n<h2 id=\"Section_1\">Understanding ALS: An Overview<\/h2>\n<h3 id=\"Section_1_SubSection_1\">Prevalence and Demographics of ALS<\/h3>\n<p>ALS is a complex neurological condition that affects individuals across all backgrounds. While it&#8217;s more common in men, women face unique challenges in diagnosis and treatment. The median age of onset is around 55 years, but cases can occur earlier or later in life<sup><a href=\"#ref1\">[1]<\/a><\/sup>. Interestingly, military veterans have a higher risk of developing ALS, though the reasons remain unclear. Genetic factors play a role in about 5-10% of cases, while the majority are sporadic<sup><a href=\"#ref2\">[2]<\/a><\/sup>.<\/p>\n<h3 id=\"Section_1_SubSection_2\">The Importance of Early Detection in ALS Management<\/h3>\n<p>Early detection of ALS is a cornerstone of our mission at ALS United Greater New York. It&#8217;s crucial for improving patient outcomes and quality of life. The diagnostic journey can be challenging, with patients often seeing multiple physicians before receiving a definitive diagnosis<sup><a href=\"#ref3\">[3]<\/a><\/sup>. <\/p>\n<div class=\"callout callout-color1 callout-left\">\n    ALS typically manifests in two forms: sporadic ALS (90% of cases) and familial ALS (10% of cases), with early symptoms including muscle twitches, cramps, and weakness.\n<\/div>\n<p>Early diagnosis allows for prompt initiation of multidisciplinary care, which has been shown to extend survival and enhance quality of life. It also enables patients to access emerging therapies and participate in clinical trials at earlier stages of the disease, potentially maximizing their benefits<sup><a href=\"#ref4\">[4]<\/a><\/sup>.<\/p>\n<h2 id=\"Section_2\">Early Signs of ALS in Females<\/h2>\n<h3 id=\"Section_2_SubSection_1\">Bulbar-Onset Symptoms: Speech and Swallowing Difficulties<\/h3>\n<p>Bulbar-onset ALS, affecting approximately 25% of patients, is particularly common in women. It manifests primarily through speech and swallowing difficulties. Early signs may include:<\/p>\n<ul>\n<li>Slight slurring of speech, especially when tired<\/li>\n<li>Difficulty swallowing (dysphagia)<\/li>\n<li>Frequent choking or coughing while eating<\/li>\n<li>Tongue muscle twitches (fasciculations)<\/li>\n<li>Emotional lability (inappropriate laughing or crying)<\/li>\n<\/ul>\n<p>These symptoms can significantly impact a person&#8217;s quality of life and social interactions, often prompting initial medical consultations<sup><a href=\"#ref5\">[5]<\/a><\/sup>.<\/p>\n<h3 id=\"Section_2_SubSection_2\">Limb-Onset Symptoms: Weakness and Coordination Issues<\/h3>\n<p>Limb-onset ALS, affecting about 75% of patients, typically manifests through progressive weakness and coordination issues in the arms and legs. Early signs may include:<\/p>\n<ul>\n<li>Difficulty with fine motor tasks (e.g., buttoning a shirt)<\/li>\n<li>Muscle weakness, particularly in hands, feet, or ankles<\/li>\n<li>Frequent tripping or falling<\/li>\n<li>Muscle twitching and cramping<\/li>\n<li>Visible muscle atrophy<\/li>\n<\/ul>\n<p>It&#8217;s important to note that pain is generally not a prominent feature in the early stages of ALS, distinguishing it from other neurological conditions<sup><a href=\"#ref6\">[6]<\/a><\/sup>.<\/p>\n<h3 id=\"Section_2_SubSection_3\">Cognitive and Emotional Changes in Early-Stage ALS<\/h3>\n<p>Cognitive and emotional changes affect up to 50% of ALS patients. These changes can include:<\/p>\n<ul>\n<li>Impairment in executive functions<\/li>\n<li>Difficulties in recognizing complex emotions<\/li>\n<li>Mild to severe depressive symptoms and anxiety<\/li>\n<\/ul>\n<p>Interestingly, despite the progressive nature of ALS, cognitive decline over time is not uniform. Some functions may remain stable, highlighting the complex nature of psychological adjustment in ALS<sup><a href=\"#ref7\">[7]<\/a><\/sup>.<\/p>\n<div class=\"callout callout-color2 callout-right\">\n    Women are more prone to bulbar-onset ALS, especially after age 60, which primarily affects speech and swallowing functions.\n<\/div>\n<h2 id=\"Section_3\">Gender Differences in ALS Presentation<\/h2>\n<h3 id=\"Section_3_SubSection_1\">Comparing Symptom Onset Between Males and Females<\/h3>\n<p>At ALS United Greater New York, we recognize the importance of understanding gender differences in ALS presentation. Women, especially those aged 60 and above, are more prone to bulbar-onset ALS, which manifests primarily through speech and swallowing difficulties. This contrasts with men, who tend to experience spinal-onset ALS with initial weakness in the limbs<sup><a href=\"#ref8\">[8]<\/a><\/sup>.<\/p>\n<h3 id=\"Section_3_SubSection_2\">Hormonal Influences on ALS Progression in Women<\/h3>\n<p>Hormonal factors play a significant role in ALS progression in women. Research suggests that endogenous estrogen exposure may have a protective effect against ALS. Women who experience menopause before age 50 are more likely to be diagnosed with ALS earlier in life<sup><a href=\"#ref9\">[9]<\/a><\/sup>. This underscores the importance of considering hormonal factors in the study and treatment of ALS in women.<\/p>\n<h3 id=\"Section_3_SubSection_3\">Genetic Factors Affecting ALS Development in Females<\/h3>\n<p>Genetic factors contribute significantly to ALS development, with sex-specific differences emerging as an important area of investigation. Certain genetic mutations associated with ALS show varying prevalence between males and females. For instance, the C9orf72 repeat expansion is more prevalent among females with ALS compared to males<sup><a href=\"#ref10\">[10]<\/a><\/sup>.<\/p>\n<div class=\"callout callout-color1 callout-left\">\n    Hormonal factors play a significant role in ALS progression in women, with endogenous estrogen potentially offering a protective effect against the disease.\n<\/div>\n<h2 id=\"Section_4\">Diagnostic Challenges for ALS in Women<\/h2>\n<h3 id=\"Section_4_SubSection_1\">Distinguishing ALS Symptoms from Other Neurological Conditions<\/h3>\n<p>Distinguishing ALS symptoms from other neurological conditions can be challenging due to overlapping clinical presentations. Key differentiating factors include the absence of sensory symptoms and the progressive nature of ALS. Advanced diagnostic tools, such as electromyography (EMG) and magnetic resonance imaging (MRI), play a crucial role in accurate diagnosis<sup><a href=\"#ref11\">[11]<\/a><\/sup>.<\/p>\n<h3 id=\"Section_4_SubSection_2\">The Role of Medical History and Physical Examinations<\/h3>\n<p>At ALS United Greater New York, we emphasize the importance of comprehensive medical history and physical examinations in the diagnostic process. Neurologists assess muscle strength, reflexes, coordination, and sensation to identify signs of both upper and lower motor neuron involvement. These examinations are crucial in distinguishing ALS from other neurological conditions with overlapping symptoms<sup><a href=\"#ref12\">[12]<\/a><\/sup>.<\/p>\n<h3 id=\"Section_4_SubSection_3\">Advanced Diagnostic Tools and Tests for Confirming ALS<\/h3>\n<p>Advanced diagnostic tools for confirming ALS include electromyography (EMG) and nerve conduction studies (NCS). These tests are essential in identifying lower motor neuron involvement, often before it becomes clinically evident. Additional techniques like repetitive stimulation and single fiber EMG can provide valuable information in challenging cases<sup><a href=\"#ref13\">[13]<\/a><\/sup>.<\/p>\n<div class=\"callout callout-color2 callout-right\">\n    Distinguishing ALS symptoms from other neurological conditions requires advanced diagnostic tools like EMG and MRI, along with comprehensive physical examinations.\n<\/div>\n<h2 id=\"Section_5\">Support and Management for Women with Early ALS<\/h2>\n<h3 id=\"Section_5_SubSection_1\">Multidisciplinary Care Approaches for ALS Patients<\/h3>\n<p>At ALS United Greater New York, we champion a multidisciplinary care approach for ALS patients. This comprehensive team includes neurologists, pulmonologists, speech therapists, occupational therapists, and mental health professionals. Together, they work to manage symptoms, improve quality of life, and potentially extend survival<sup><a href=\"#ref14\">[14]<\/a><\/sup>.<\/p>\n<h3 id=\"Section_5_SubSection_2\">Lifestyle Adaptations and Assistive Technologies<\/h3>\n<p>As ALS progresses, lifestyle adaptations and assistive technologies become crucial for maintaining independence and quality of life. These can include mobility aids, communication devices, home modifications, and specialized eating utensils. These adaptations not only address physical challenges but also contribute significantly to mental well-being by fostering a sense of control and independence in daily life<sup><a href=\"#ref15\">[15]<\/a><\/sup>.<\/p>\n<h3 id=\"Section_5_SubSection_3\">Emotional Support and Mental Health Resources<\/h3>\n<p>Psychological support services play a crucial role in managing the emotional challenges faced by individuals with ALS. At ALS United Greater New York, we offer various support mechanisms, including support groups and counseling services. We understand the emotional impact of an ALS diagnosis and work tirelessly to provide comprehensive support to both patients and caregivers<sup><a href=\"#ref16\">[16]<\/a><\/sup>.<\/p>\n<div class=\"callout callout-color1 callout-left\">\n    Multidisciplinary care approaches, including neurologists, pulmonologists, and therapists, are essential for managing ALS symptoms and improving quality of life.\n<\/div>\n<h2 id=\"conclusion\">Conclusion<\/h2>\n<p>Understanding the early signs of ALS in females is crucial for early detection and effective management of the disease. At ALS United Greater New York, we&#8217;re committed to supporting individuals affected by ALS through every stage of their journey. Our WALK ALS event (<a href=\"https:\/\/als-ny.blackbaudwp.com\/get-involved\/events\/walk-als\/\">https:\/\/als-ny.blackbaudwp.com\/get-involved\/events\/walk-als\/<\/a>) is just one of the many ways we bring our community together to raise awareness and funds for ALS research and support.<\/p>\n<p>Your involvement can make a real difference in the lives of those affected by ALS. Together, we can work towards better outcomes and improved quality of life for ALS patients. <a href=\"https:\/\/secure.als-ny.org\/site\/Donation2?df_id=1500&#038;mfc_pref=T&#038;1500.donation=form1\">Donate Now<\/a> to support our mission and help us continue providing essential services to the ALS community.<\/p>\n<div class=\"key-takeaways\"><b>Key Takeaways<\/b><\/p>\n<ol>\n<li>ALS affects approximately 5 out of every 100,000 people worldwide.<\/li>\n<li>Early detection is crucial for improving patient outcomes and quality of life.<\/li>\n<li>Women are more prone to bulbar-onset ALS, especially after age 60.<\/li>\n<li>Hormonal influences play a significant role in ALS progression in women.<\/li>\n<li>Multidisciplinary care approaches are essential for managing ALS effectively.<\/li>\n<\/ol>\n<\/div>\n<div id=\"references\"><b>References<\/b><\/p>\n<ol>\n<li id=\"ref1\"><a href=\"https:\/\/www.nature.com\/articles\/d42473-021-00336-8\">https:\/\/www.nature.com\/articles\/d42473-021-00336-8<\/a><\/li>\n<li id=\"ref2\"><a href=\"https:\/\/www.nature.com\/articles\/s41598-023-27863-2\">https:\/\/www.nature.com\/articles\/s41598-023-27863-2<\/a><\/li>\n<li id=\"ref3\"><a href=\"https:\/\/www.nature.com\/articles\/d42473-021-00336-8\">https:\/\/www.nature.com\/articles\/d42473-021-00336-8<\/a><\/li>\n<li id=\"ref4\"><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/amyotrophic-lateral-sclerosis\/diagnosis-treatment\/drc-20354027\">https:\/\/www.mayoclinic.org\/diseases-conditions\/amyotrophic-lateral-sclerosis\/diagnosis-treatment\/drc-20354027<\/a><\/li>\n<li id=\"ref5\"><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/16729-amyotrophic-lateral-sclerosis-als\">https:\/\/my.clevelandclinic.org\/health\/diseases\/16729-amyotrophic-lateral-sclerosis-als<\/a><\/li>\n<li id=\"ref6\"><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/amyotrophic-lateral-sclerosis\/symptoms-causes\/syc-20354022\">https:\/\/www.mayoclinic.org\/diseases-conditions\/amyotrophic-lateral-sclerosis\/symptoms-causes\/syc-20354022<\/a><\/li>\n<li id=\"ref7\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8296637\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8296637\/<\/a><\/li>\n<li id=\"ref8\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0022510X23001582\">https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0022510X23001582<\/a><\/li>\n<li id=\"ref9\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8506649\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8506649\/<\/a><\/li>\n<li id=\"ref10\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7279172\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7279172\/<\/a><\/li>\n<li id=\"ref11\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK556151\/\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK556151\/<\/a><\/li>\n<li id=\"ref12\"><a href=\"https:\/\/emedicine.medscape.com\/article\/1170097-clinical\">https:\/\/emedicine.medscape.com\/article\/1170097-clinical<\/a><\/li>\n<li id=\"ref13\"><a href=\"https:\/\/www.massgeneral.org\/neurology\/als\/patient-education\/diagnosing-als\">https:\/\/www.massgeneral.org\/neurology\/als\/patient-education\/diagnosing-als<\/a><\/li>\n<li id=\"ref14\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10585945\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10585945\/<\/a><\/li>\n<li id=\"ref15\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4433000\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4433000\/<\/a><\/li>\n<li id=\"ref16\"><a href=\"https:\/\/www.psychiatrist.com\/jcp\/psychological-burden-of-als-and-tools-we-can-use-to-help\/\">https:\/\/www.psychiatrist.com\/jcp\/psychological-burden-of-als-and-tools-we-can-use-to-help\/<\/a><\/li>\n<\/ol>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u00cdndice Resumen Comprensi\u00f3n de la ELA: una descripci\u00f3n general Prevalencia y demograf\u00eda de la ELA La importancia de la detecci\u00f3n temprana en el tratamiento de la ELA Signos tempranos de ELA en mujeres: una visi\u00f3n detallada\u2026<\/p>","protected":false},"author":60,"featured_media":6032,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[70],"tags":[],"class_list":["post-5995","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-resources"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/als-ny.blackbaudwp.com\/es\/wp-json\/wp\/v2\/posts\/5995","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/als-ny.blackbaudwp.com\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/als-ny.blackbaudwp.com\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/als-ny.blackbaudwp.com\/es\/wp-json\/wp\/v2\/users\/60"}],"replies":[{"embeddable":true,"href":"https:\/\/als-ny.blackbaudwp.com\/es\/wp-json\/wp\/v2\/comments?post=5995"}],"version-history":[{"count":7,"href":"https:\/\/als-ny.blackbaudwp.com\/es\/wp-json\/wp\/v2\/posts\/5995\/revisions"}],"predecessor-version":[{"id":6035,"href":"https:\/\/als-ny.blackbaudwp.com\/es\/wp-json\/wp\/v2\/posts\/5995\/revisions\/6035"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/als-ny.blackbaudwp.com\/es\/wp-json\/wp\/v2\/media\/6032"}],"wp:attachment":[{"href":"https:\/\/als-ny.blackbaudwp.com\/es\/wp-json\/wp\/v2\/media?parent=5995"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/als-ny.blackbaudwp.com\/es\/wp-json\/wp\/v2\/categories?post=5995"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/als-ny.blackbaudwp.com\/es\/wp-json\/wp\/v2\/tags?post=5995"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}